01
How are nitrogen and carbon cycles quantitatively linked in the face of resource limitations? For this, we are developing cultivation technologies and combining them with various omics and quantitative approaches.
WELCOME TO THE WU LAB OF MICROBES
In the Wu Lab, we study the tiny organisms that make the planet the way it is today. We combine quantitative experiments with computational approaches to bridge small-scale interactions with large-scale phenomena in space and time.
Research
Wu Lab attempts to link the molecular and cellular interactions of microbial cells to biogeochemistry and evolution, in order to contribute to addressing two basic questions:
02
How did genetic diversity emerge in the prokaryotes and propagate across eukaryotes? For this, we are combining bioinformatics and protein biochemistry, with a recent focus on the central dogma as well as its hijacking by mobile genetic elements.
News & Events
Latest Publications
RNA-guided RNA silencing by an Asgard archaeal Argonaute.
In this paper, we show that an Asgard archaeal Argonaute mediates RNA-guided RNA silencing, providing new insights into the origin and diversification of eukaryotic RNA silencing pathways.
Read MoreSerial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor.
Feng Y, Ding J, Lin Y, Cui D, Li K, Zheng D, Cai Z, Bell SD, Wu F#.
Read MoreViperin immunity evolved across the tree of life through serial innovations on a conserved scaffold.
Shomar H*, Georjon H*, Feng Y, Olympio B, Tesson F, Cury J, Wu F# & Bernheim A#.
Read MoreEvolutionary diversification of methanotrophic ANME-1 archaea and their expansive virome.
Laso-Perez R*,#, Wu F*,#, Crémière A, Speth DS, Zhao K, Magyar JS, Krupovic M# & Orphan VJ#.
Read More